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Notify patients that: Tramadol Hydrochloride Prolonged-Launch is for oral use only and may be swallowed full. The capsule should not be chewed, dissolved, crushed or split. Tramadol Hydrochloride Prolonged-Release may perhaps trigger seizures and/or serotonin syndrome with concomitant utilization of serotonergic agents (such as SRIs, NRIs, and trip